Signature_score

10

0

ns

IMEscore

ns

CD_8_T_efector

ns

imune_Checkpoint

ns

CESC

Anegen_processing_machinery

**

Signature_score

MESCOreA

**

-30-20-10 0 102

TMESCOM

ns

Mismatch_Repal

Nucleotide_exason_repal

**

GD_8_T_efecto

ns

ONA_damage_response


fxmune_Checkpoint

ns

ONA JepicNon

ns

OLBC

Antigen_ processing_suachinery

ns

Signature

Base_exasion_repa

ns

Signature_score

IMESCOreA

PAR_F_TBRS

ns

-10 2

14

Mismatch_Repair

YME SOON

ns

Nucleotide_exasion_repair

1

ns

EMTS

LD_8_T_effector

Di

ONA_damage_response

EMI2

prune_Checkpoin

ns

EMYS

HNSC

M

IME scoreB

TMEcluster

Antigen_processing_aukhinery

ONA sepicatos

ns

Signature

Base_exdsion_Repa

ns

ns

Signature_score

IMESCoreA

ns

ns

-20 -19

POR_F_IBRS

ns

TMEscore

ns

Msnach_Repal

ns

Nucleol de_excision_repair

EMTS

Di

BLCA

Lo_8_T_effecty

EMT2

2

ns

0

printune_Checkpoint

ns

ONA_damage_response

EMTS

Signature_score

ORA Jeproto

2

KIRP

30

8

TMEcluster

Antigen_processing_machinery

Base_excision_jepal

IMEscoreB

Signature

ns

Signature_score

IMEscore

IMESCoreA

ns

0

-19

POR FIBRS

CO_8_T_effector

A

Msmach_Repal

ns

presune_Checkpoint

-

TMEScore

Di

Audeolde_excision_repair

EMT1

EN

10

Antgen_processing_machinery

ns

HO

10_8_1_effecty

ONA_damage_response

EM12

Signature_score

0

CHOL

ns

Kimune_Checkpoin

ns

EMT3

-10

IMESCOBA

LIHO

TMEcluster

ns

Mogen_processing_machines

ONA Jepi onion

IMEscores

Mismatch_Repa

ns

Signature

Base _excision_epal

ns

Nucleotide_exasson_sepa

ns

ns

Signature_score

IMEscore

N

**

ns

CO_8_T_effector

ns

-20 -10 0 10

MESCO SMA

PORFIBR

DNA damage_response

ns

ns

Mismaich_Repal

ns

BUTune_Checkpoint

ns

Nucleo lide_excision_repair

EMT1

ESCA

DNA_replicaNon

ns

IMEScorp

Di

20

Antigen_processing_machinery

EMTZ

Di

ns

Signature

LD_8_T_efecto


ONA_damage_response

Signature_score

0

ns

Base_exason_repal

wirune_Che apoin

TMESCOBA

ns

ns

MESO

Argen_processing_suachinery


ONA Jepicatio

ns

EMTS

JA

Pan F_TBRs

IMEscoreB

TMEcluster

Mismatch_Repa

EN

ns

10

Signature

Base_excision_sepal

EMTS

Signature_score

TMESOS

Nucleotide_excision_spa

Di

-10

SMESONOA

CO_8_T_effector

ns

ns

EMT2

ns

Mismatch_Repal

PAR.F.TERS

ORA_damage respons

ns

minune_Checkpoint

ns

EMT 3

$

ruceobde_excision_repair

EMT1

KICH

ONA_sep Fontos

TMEcluster

LD_8_T_efe do

Di

Signature

ONA_ damage_response

EM12

10

Antigen_processing_machinery

ns

TMESCOPER


Signature_score

0

Base_exosion_sepak

ns

10

mitune_Checkpoint

ONA JeDicatio

ns

EMTS

·10

A

Pan_F_TBRs

ns

PCPG

TMEcluster

Anegen_processing_suachinery

TME 80008

Mismatch_Repal

DA

Signature

Signature

ns

ns

ns

Base_excision_epal

0%

EMT1

BRCA

Signature_score

IMESCORSA

DA

0

PAR F_TERS

ns

IMESOre

Aucieos de_excision_sepal

ns

Lmp

CO_8_T_effector

ns

ns

*

-20 -10

Mismatch_Re pal

ONA_damage_response

EMT2

Signature

ns

ns

EMT 3

Signature_score

**

MESCO

Nucleotide_exason_se pai

EMT

serune_Checkpoint

TMEcluster

Antigen_processing_machinery

ORA_replication

TMESCOreB

-20-10 0 10 20 30

LAML

EN

EMIZ

ns

Signature

Lo_8_T_effector

ONA_damage_response

ns

Signature_score

Base_excision_repal

IMEscore

ns


prisune_Checkpoin

10 -5 0 5 10 15

IMEscoreA

ns

ns

ONA JeDioNon

EMTS

Løxp

Pan F_TBRs

CO_8_T_efecto

ns

SARC

TMEcluster

Antigen _processing_machinery


Msnach_Repa

ns

20

Signature

ns

EMTS

ns

Base_exasion_repal

TMEsaxeB

Irune_Checkpoin

ns

Signature_score

0

IME score

Nudeolde_excision_sepal

ns

COAD


:

IMESCOPOA

Ansgen_ processing, machinery

-0

Msnatch_Ropa

PARF_TBRS

ns

P

CO.8_1_effector

ns

ORA_damage_response

EM12

ns

ns

Signature_score

Porune_Checkpoint

TME scoreA

TMEScore

ns

Aucieolde_excision_repay

EMTS

ns

ns

EM13

EN

LUAD

ONA_repi ation

TMEcluster

Antigen_processing_machinery

-30-20-10 0 10 20 30

0

Lo_BY_effector

Di

ns

IMEscores

Signature

.-

Mismatch Repas

ns

EMIZ

Base_excision_repair

0

10

TMEscore

Nucleotide_exason_sepa


4

prisune_Checkpoint

5%

O/e_damage_response

Signature_score

ns

EMTS

= 10

Te

MESCODA

ns

Ho

Pan F_TBAs

Co ___ efecto

ONA_damage_response


TGCT

DNA_Replication

TMEcluster

Abgen_processing_frachin ery

05

IMEscore8

Mismatch_Repa

ns

4

Signature

0

Base_excision_epal

TMEcluster

ns

ns

amiune_Checkpoint

ns

Signature_score

ns

TMEcluster

IMEscore


Nucleo tide_excision_repa

ns

EMT1

DNA replication

GBM

IMESCoreA

ns

10

Antigen_processing, machinery

ns

Signature

POR_F_TBRs

CO_8_T_effector

ORA_darrage_esponse

ns

EMT2

Mamaich_Repair

Signature_score

0

Base_exo son repair

ns

**

Rorune_Checkpoint

EM13

Pan_F_TBRS

TMESCOPE

Nudeolde_excision_repair

EMTY

-10

IMRE scoreA

Di

Antigen_processing_machinery

ONA replication

TMEcluster

ns

TMEscores

Mismatch_ Repa

Signature

**

LD_8_1_effects

ONA_damage_response

Base_excision_repal

3 ME 800

Nucleotide_exason_sepa

A

ns


EMT 3

ns

EMIZ

ns

Signature_score

prisune_Checkpoint

TMESONRA

Antigen_processing_frchinery

-

DNA_sepi onion

ns

EMTS

-20-10 0 10 20

LA

ns

4%

pan __ TBRs

CD_6_1_effector

DNA_damage_response


EMT2

UCEC

TMEcluster


Signature

Base_excision_repair

IMEscoreB

Mismatch_Repa

fortune_Checkpoint

EMT3

IMEscore

ns

EMT1

ns

Nucleotide_excision_repa

ns

KIRC

ONA sepiicition

TMEcluster

Signature_score

IMESCORA

ns

Pan_F_IBRS

ns

CO_8_T_efectos

ns

ORA_ darrage_respons

ns

EMT2

ns

Anigen_processing, machinery

ns

TME scoreB

Signature

-20-10 0 10 20

Mismach_Repair

ns

ns

EM13

Signature_score

Base_extsion_epair

ns

ns

ns

IME Score

Nudeolde_excision_repair

EMT1

Rorune_Checkpoint

MAREscoreA

Anegen_processing_machinery

ORA replication

-20-10 0 10 20

Pan_F_TBRS

PRAD

TMEcluster

Di

ns

ns

D_8_T_efecty

DNA_damage_response

ns

EMIZ

Signature

Base_excision_repal

**

TMESCORN

TMESONS

ns

Nucleos de_excision repay

ns

EMT

ns

EMTS

Signature_score

imune_Checkpoint

20-10 0 10 20

TMESCORRA

ns

15


**

Antigen_processing_machinery

Drei sepi onion

ns

CD_B_1_effecto

-20-10

**

Pan __ TBRs

DNA damage_response

ns

EMT2

TMEcluster

Signature

Base_excision_repas


IMEscore8

IMESCOR

ns

Mismatch_He pal

EMT1

faxune_ Checkpoint

ns

EMY 3

TMEcluster

ns

Aucreodide_exdsson_s pal

Di

09

MESONOA

EMT2

ns

GG

Antigen_processing, machinery

ORA sepiciNon

CO_8_T_effector

**

**

3

Signature

PAR_F_TBRS

ORA_damage_response

ns

Signature_score

Base_excision_repais

IME scoreB

Mismatch_Repair

ns

ns

EMT3

SMEscored

ns

Nucleotide_excision_repair

EMT1

Brunet_Checkpoin

ONA sepioNon

KY

10 -5 0 5 10

SKCM

TMEcluster

ns

Pan F_TBRs

A

ns

DNA damage_response

-

EM12

Antigen_Processing_machinery

ns

pose_exason_repal

TMESONES

Massach_Repair

Signature

ns

Signature_score

IMESCOre

Nudeolde_ercision_repa)

EMT1

DNA replication

ns

EMIS

ns

LØKP

20-10 0 10 20

TMESCOreA

-20-19

00_8_1_effector

EMT2

ns

PanF_TBRs

DNA damage_response

TMEcluster

Signature

Base_excision_repair

ns

IME scoreB

Mama_ Repa

a

IMEscore

.

miune_Checkpoin

Aucieos de_excision_repa

EMT1

ns

LUSC

ONA.repli cation

EM73

IMEscoreB

TMEcluster

ns

20

Antigen_ processing, machinery

ns

3

Signature

PAR F_TBRS

CO_8_T_effector

EMT2

10

Base_excision_repair


EMTY

ns

O/H_damage_respons

0

ns

prisune_ Checkpoint

ns

EMT 3

Signature score

-10

MESCOMBA

Pan FIBRE

ns

20

THCA

EMIZ

Antigen_processing_machinery

ORA_replicaon

TMESCOPER

TMEcluster

Mismaich_ Repal

ns

ns

Signature


Base_excision_repal

**

TMEscore

W

Signature_score

Nucleo tide_excision_epal

ns

EMT1

EMTS

0

..

IMESCoreA

ns

ns

$

Pan_F_TBRs

GD_8_T_efecto

ns

EMT2

IMEsoreB

TMEcluster

10

Mansich_Repal

ONA damage_Response

**

EM73

T ME score

Nudeos de_excision_sepa

EN

EMT!

Harune_Checkpoin

PAAD

DNA replication

TMEscoreB

TMEcluster


CO_8_1_effector

ORA_damage_response

**

EM12

Antigen_ processing, machinery

**

Signature

Base_excision_repair

wwwune_Checkpoint

ns

0

EMIS

Signature_score

SME SOOFBA

ns

UCS

Antigen_processing_machinery

ONA_repi ONtion

TMEcluster

20 -10

Pan_F_TBRS

ns

Mismatch_Repal

Signature

Signature_score

Base_excision_repair

**

TMEscores

TMEScore

**

Nucleotide_excision_epal

EMT1

-10 0 10 20 30

ns

MES

ns

ns

EMT2

ns

Msmatch_Repair

Pan_F_TBRs

CD_6_1_efe co

DNA_damage_response


**

ns

EMT1

ns

TME Score

Nudeolde_excision_repair

Hatune_Checkpoint

EM73

20

READ

TMEcluster

CO_8_T_effector

ns

EM12

Ansgen_processing, machinery

ns

MA sopication

TME SOO JeB

Signature

ONA_damage_Response

10

0%

0

ns

dase_excision sepal

profune_Checkpoint

ns

EM13

Signature_score

IMRE SCOPEA


**

Antigen_processing_machinery

20 -10

ns

ns

Of_repli cation

TMEcluster

TMEscores

Mismatch, Re pal

ns

Pan_F _TBRS

Signature

Base_excision_repair

**

ns

TMESCOR

TMESCORRA

Nucleotide_exosopp

EMT

**

ns

Pan_F_TBRS

ns

CO_8_1_efecto

*

Mismatch_Repair

ONA_damage_response

ns

EMI2

ns

ns

EMTS

Immune_Checkpoin

ns

Nucleotide_excision_repair

ns

EMY3

STAD

ONA sepiciNon

TMEcluster


DNA_damage_response

EMT2

20

Anigen processing,machinery

ns

ns

TME StoreB

ns

Signature

Signature_score

dase_exason_repair

DNA replication

ns

EM13

SMEscored

ns

Løxp

Pan_F_TBRS

**

TMEcluster

IMESCORB

March_Repas


Signature

Base_excision_repair

TMESONe

-

Nucleosde_excision_repal

EMT 1

Pan F_TBRS

ns

Løp

Co ___ effector

DNA_dansage_response

EMT2

EMTS

smrtune_Checkpoint

**

ns

THYM

Antigen_processing, machinery

ns

ORA. spliciNon

ns

EMT3

C

EMT2

TME ScoreB

TMEcluster

Signature

Base_excision_sepal


EM13

Signature_score

ns

ns

20 -10

SMEscoreA

TMEcluster

Mamaich, Repal

ns

Pan FIBRs

TMESONES

ns

IMEscore

Nudeosde_excision_repal

EMT1

Co ___ effector

ns

DNA damage_response

EMI2

smrtune_Checkpoint

ns

ns

EMTS

UVM

10

Antigen_ processing, machinery

ns

ONA.repli cation

TMEcluster

-

IMEscoreB

5

Signature

ns

Signature score

0

TME SCOMPA

ns

Base_excision_repair

Mamaich Repas

ns

Pan_F_TBRS

ns

Løp

ns

A

IMEScore

ns

Nudeolde_excision_sepal

ns

EMT3

co_8_T_effector

DNA damage_Response

EMTZ

Immune_Checkpoint

OM repli cation

ns

EM73

Antigen_ processing, machinery

TMEcluster

-

IMEscoreB

Signature

Base_excision_repair

ns

TME ScoreA

Pan __ TBRS

p

Mismatch, Repair

EMT3

ns

Nucleotide_excision repair

DNA damage_response

EMT2

DNA replication

EM73

Signature

Base_excision_repair

.

ns

TME score

TMEcluster

Pan F TERS

ns

LExp

ns

EMT1

**

EMT2

EMT3

TME storeB

TMEcluster

*

*

a

a

*

a

a

a

a

*

a

a

a

a

*

a

a

0

5

a

a

*

*

*

a

a

*

*

*

a

a

*

a

a

a

a

a

a

*

a

a

*

a

a

a

a

*

a

a

*

*

a

a

*

a

a

*

0

a

a

a

a

*

a

a

*

a

a

*

*

a

a

*

a

a

a

a

*

*

a

a

*

*

*

*

*

0

a

a

*

*

a

*

*

a

a

*

*

*

*

0

a

a

*

a

a

a

a

*

*

*

a

a